搜索结果

Search Results for " cmp kinase "

Targets Recommended: Tyrosine Kinases JAK

抑制剂 & 化合物

天然产物

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T3080	Pyridone 6 Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,吡啶酮6,JAK Inhibitor I	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Pyridone 6 (JAK Inhibitor) 是一种泛JAK 抑制剂，有效抑制 JAK 激酶家族，对JAK2、TYK2、JAK3和JAK1的IC50分别为 1、1、5 和 15 nM。
T8735	Sulbactum Sodium 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸	Others	Others
	Sulbactum Sodium (5'-CDP) 由胞苷一磷酸 (CMP) 或尿苷一磷酸 (UMP) 通过磷酸基团的转移在尿苷酸激酶 (UMPK) 酶的催化下合成。
T36300	Uridine-5’-monophosphate (sodium salt hydrate)
	Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements. 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002)

化合物

Pyridone 6

Cat.No: T3080

Synonym: Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,吡啶酮6,JAK Inhibitor I

Target: Tyrosine Kinases, JAK

Sulbactum Sodium

Cat.No: T8735

Synonym: 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸

Target: Others

Uridine-5’-monophosphate (sodium salt hydrate)

Cat.No: T36300

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T4731	2'-Deoxycytidine-5'-monophosphoric acid dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) 被用作尿苷单磷酸(UMP)或胞苷单磷酸(CMP)激酶的底物，形成 dCDP，在磷酸化成 dCTP 后支持 DNA 的生物合成。

天然产物

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

2'-Deoxycytidine-5'-monophosphoric acid

Cat.No: T4731

Synonym: dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cytidine mon...	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi...
TMPH-02964	UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9DBP5.
TMPH-00603	Cytidylate kinase Protein, E. coli, Recombinant (His & SUMO) Cytidine monophosphate kinase,CMP kina...	E. coli	E. coli
	ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.